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Evaluating Electrostatic Contributions to Binding with the Use of Protein Charge Ladders

✍ Scribed by Gao, J.; Mammen, M.; Whitesides, G. M.


Book ID
121156094
Publisher
American Association for the Advancement of Science
Year
1996
Tongue
English
Weight
235 KB
Volume
272
Category
Article
ISSN
0036-8075

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## Abstract The method of solution of the nonlinear Poisson–Boltzmann equation was used to calculate electrostatic energy of binding of various aromatic ligands with DNA oligomers of different length. Analysis of the electrostatic contribution was made in terms of a two‐step DNA binding process: fo