✦ LIBER ✦

Eukaryotic transcription factors

✍ Scribed by Oleg L. Polyanovsky; Alexander G. Stepchenko

Publisher: John Wiley and Sons
Year: 1990
Tongue: English
Weight: 649 KB
Volume: 12
Category: Article
ISSN: 0265-9247
DOI: 10.1002/bies.950120503

No coin nor oath required. For personal study only.

✦ Synopsis

Many nuclear proteins have been found recently to interact with short conserved sequences which are involved in regulating the transcription of various genes. Nuclear transcription factors may be arbitrarily subdivided into two groups, ubiquitous and tissue-specific. The transcription of one gene is usually regulated by several factors which interact with different sequences located either in the promoter region of the gene or outside it. The appearance or disappearance of transcription factors for some genes corresponds to certain phases of cell differentiation or dedifferentiation and even to individual stages of the cell cycle.

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