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Eukaryotic DNA primase appears to act as oligomer in DNA-polymerase-α–primase complex

✍ Scribed by Vladimir N. PODUST; Olga V. VLADIMIROVA; Elena N. MANAKOVA; Olga I. LAVRIK

Book ID
115129296
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
718 KB
Volume
206
Category
Article
ISSN
1432-1327

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Mutated constituents of the DNA replication complex might contribute to the mutational load of the genome during tumor development by impairing DNA synthesis as well as cell cycle-related control of DNA replication. To prove or disprove this hypothesis, we looked for mutations in the cDNA sequences