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Ets transcription factors ER81 and Elk1 regulate the transcription of the human presenilin 1 gene promoter

✍ Scribed by Martine Pastorcic; Hriday K. Das

Book ID
117386191
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
817 KB
Volume
113
Category
Article
ISSN
0169-328X

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Overexpression of the HER2/Neu receptor is correlated to a poor prognosis in tumor patients and leads to stimulation of mitogen-activated protein kinase (MAPK) signaling pathways, which in turn activate transcription factors, such as the ETS protein ER81. Here, we have analyzed whether, on the other