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Ethyl-3,4-diaroyl-2-cyanobutyrate: A Synthon for novel heterocycles

✍ Scribed by Adivireddy Padmaja; Thalari Payani; Konda Mahesh; Venkatapuram Padmavathi

Publisher
Journal of Heterocyclic Chemistry
Year
2009
Tongue
English
Weight
104 KB
Volume
46
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

magnified image A new class of aminopyrazolones, aminoisoxazolones, aminopyrimidinones, and thioxopyrimidinones were synthesized from Michael adduct, ethyl‐3,4‐diaroyl‐2‐cyanobutyrate, on reaction with different nucleophiles, hydrazine hydrate, hydroxylamine hydrochloride, and urea derivatives. J. Heterocyclic Chem., (2009).

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ChemInform Abstract: Substituted Ethyl 2
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Substituted Ethyl 2-Acyl-3-amino-6-methylthieno(2,3-b)pyridine-4carboxylates as Synthons for Novel Heterocycles. -Title compounds of type (III) provide novel heterocyclic compounds (V) with diketene-acetone (IV). Except for (Vb), further reaction with (IV) is possible leading to novel tetracyclic co