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Ethanol upregulates the expression of p21WAF1/CIP1 and prolongs G1 transition via a p53-independent pathway in human epithelial cells

โœ Scribed by Guo, Wentong; Baluda, Marcel A; Park, No-Hee


Book ID
110060883
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
388 KB
Volume
15
Category
Article
ISSN
0950-9232

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p21 WAF1/Cip1 is an inhibitor of cdk/cyclin complexes, and thus regulates the cell cycle. p21 is also related to cell differentiation and is regulated by wild-type p53, although p53-independent regulatory pathways have been proposed. In order to analyse p21 expression as well as its relationship wit