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Ethanol Enhances Activation-Induced Caspase-3 Dependent Cell Death in T Lymphocytes

✍ Scribed by Sujata Kelkar; Qing Dong; Yinghua Xiao; Swati Joshi-Barve; Craig J. McClain; Shirish S. Barve

Book ID: 109123126
Publisher: John Wiley and Sons
Year: 2002
Tongue: English
Weight: 656 KB
Volume: 26
Category: Article
ISSN: 0145-6008
DOI: 10.1111/j.1530-0277.2002.tb02547.x

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Mitochondria play a critical role in cell death by releasing apoptogenic factors, such as cytochrome c and apoptosis-inducing factor (AIF), from the intermembrane space into the cytoplasm. Because mitochondrial dysfunction has been shown to be involved in several neurodegenerative diseases, mitochon