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Estrogen receptor-α regulates SOCS-3 expression in human breast cancer cells

✍ Scribed by Jason Matthews; Tova Almlöf; Silke Kietz; Jörg Leers; Jan-Åke Gustafsson

Book ID
116291015
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
304 KB
Volume
335
Category
Article
ISSN
0006-291X

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## Abstract We have shown previously that withaferin A (WA), a promising anticancer constituent of Ayurvedic medicine plant __Withania somnifera__, inhibits growth of MCF‐7 and MDA‐MB‐231 human breast cancer cells in culture and MDA‐MB‐231 xenografts in vivo by causing apoptosis. However, the mecha