## Abstract The cyclinβdependent kinase inhibitor protein p21^Waf1/Cip1^ is a potent tumor suppressor. Here, we demonstrate that estradiol regulates the p21^Waf1/Cip1^ gene. Estradiol induces p21^Waf1/Cip1^ mRNA expression within 30β60βmin independent of new protein synthesis in the estrogen recept
The liver receptor homolog-1 regulates estrogen receptor expression in breast cancer cells
β Scribed by Paul T. R. Thiruchelvam; Chun-Fui Lai; Hui Hua; Ross S. Thomas; Antoni Hurtado; William Hudson; Andrew R. Bayly; Fiona J. Kyle; Manikandan Periyasamy; Andrew Photiou; Alan C. Spivey; Eric A. Ortlund; Richard J. Whitby; Jason S. Carroll; R. Charles Coombes; Laki Buluwela; Simak Ali
- Publisher
- Springer US
- Year
- 2010
- Tongue
- English
- Weight
- 758 KB
- Volume
- 127
- Category
- Article
- ISSN
- 0167-6806
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