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Estrogen receptor, progesterone receptor, and HER-2/neu protein in breast cancers from pregnant patients

โœ Scribed by Richard M. Elledge; Daniel R. Ciocca; Gregory Langone; William L. McGuire


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
802 KB
Volume
71
Category
Article
ISSN
0008-543X

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## Abstract Overexpression of Her2/neu is implicated in the development of resistance to the antiestrogen tamoxifen (TAM) that exerts its inhibitory effect through interaction with estrogen receptor (ER). Whereas Her2/neu and ER are believed to be important cell survival/death factors in human brea