𝔖 Bobbio Scriptorium
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Estrogen receptor gene amplification is found in some estrogen receptor-positive human breast tumors

✍ Scribed by Mónica Nembrot; Brenda Quintana; José Mordoh


Book ID
115763010
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
752 KB
Volume
166
Category
Article
ISSN
0006-291X

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Estrogen regulated expression of the p21
✍ Soma Mandal; James R. Davie 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 183 KB

## Abstract The cyclin‐dependent kinase inhibitor protein p21^Waf1/Cip1^ is a potent tumor suppressor. Here, we demonstrate that estradiol regulates the p21^Waf1/Cip1^ gene. Estradiol induces p21^Waf1/Cip1^ mRNA expression within 30–60 min independent of new protein synthesis in the estrogen recept