A novel gene STYK1/NOK is upregulated in estrogen receptor-alpha negative estrogen receptor-beta positive breast cancer cells following estrogen treatment
β Scribed by K. Sean Kimbro; Kaitlin Duschene; Margeret Willard; Jodi-Ann Moore; Shalonda Freeman
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 187 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0301-4851
No coin nor oath required. For personal study only.
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## Abstract The cellβsurface glycoprotein KAI1 suppresses tumor growth and metastasis in various animal models. Downregulation of KAI1 has been implicated in the progression of cancer. However, the mechanisms of KAI1 inactivation are poorly understood. This is the first study that investigates expr
With interest I read the article by Christgen et al. that was recently published under the Fast Track heading in the International Journal of Cancer. 1 The major reported findings, nicely summarized in the article's title, are that (a) KAI1/CD82 is downregulated in 77% of human breast carcinomas and