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Estrogen receptor dependent gene expression by osteoblasts – Direct, indirect, circumspect, and speculative effects

✍ Scribed by Michael Centrella; Thomas L. McCarthy


Book ID
116892712
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
272 KB
Volume
77
Category
Article
ISSN
0039-128X

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## Abstract Estrogen receptor (ER)‐α can signal either via estrogen response element (ERE)‐mediated pathways or via alternate pathways involving protein–protein or membrane signaling. We previously demonstrated that, as compared to wild type (WT) controls, mice expressing a mutant ER‐α lacking the