Estrogen-induced lysosomal proteases sec
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Henri Rochefort; Françoise Capony; Marcel Garcia; Vincent Cavaillès; Gilles Frei
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Article
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1987
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John Wiley and Sons
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English
β 893 KB
In an attempt to understand the mechanism by which estrogens stimulate cell proliferation and mammary carcinogenesis, metastatic human breast cancer cell lines (MCF7, ZR75-1) were found to secrete a 52,000 dalton (52K) protein under estrogen stimulation. Following its purification to homogeneity, th