Gallbladder disease is more prevalent in women than men. Estrogen therapy has been associated with an increased incidence of gallbladder disease in both sexes. Further, increased progesterone levels have been implicated in impairment of gallbladder motility in pregnancy. Because sex hormones often e
Estrogen and progesterone receptors in gallbladder cancer
β Scribed by Satoshi Nakamura; Hiroyuki Muro; Shouhachi Suzuki
- Book ID
- 112756081
- Publisher
- Springer
- Year
- 1989
- Tongue
- English
- Weight
- 700 KB
- Volume
- 19
- Category
- Article
- ISSN
- 1436-2813
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Cancerous tissue from 86 patients with primary gastric cancer were examined for the presence of receptors for estrogen (ER) and progesterone (PgR). ER and PgR were present in 8 (15.4%) and 5 (9.6%), respectively, of 52 male patients, 9 (26.6%) and 7 (20.6%), respectively, of 34 female patients, a to
Cytosolic receptors for estrogen and progesterone were assayed in 50 gallbladders from 29 women and 21 men who had cholecystectomies because of cholelithiasis. High-affinity (equilibrium dissociation constant, KD = 0.46 2 0.23 nmol/L of 24 cases) estrogen receptors were detected in 20 of 29 gallblad