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Estradiol-induced protection against ischemia-induced heart mitochondrial damage and caspase activation is mediated by protein kinase G

✍ Scribed by Ramune Morkuniene; Odeta Arandarcikaite; Laima Ivanoviene; Vilmante Borutaite

Book ID: 113484553
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 456 KB
Volume: 1797
Category: Article
ISSN: 0005-2728
DOI: 10.1016/j.bbabio.2010.03.027

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## Abstract Excitotoxicity and cell death induced by glutamate are involved in many neurodegenerative disorders. We have previously demonstrated that excitotoxicity induced by millimolar concentrations of glutamate in hippocampal slices involves apoptotic features and glutamate‐induced glutamate re