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Estimation of the relationship between caspase-3 expression and clinical outcome of Burkitt's and Burkitt-like lymphoma

✍ Scribed by Yuko Nomura; Shiro Yoshida; Kennosuke Karube; Morishige Takeshita; Shinichi Hirose; Shigeo Nakamura; Tadashi Yoshino; Masahiro Kikuchi; Koichi Ohshima

Book ID
108584233
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
203 KB
Volume
99
Category
Article
ISSN
1347-9032

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The 3p14.2 chromosome region, which contains the FHIT gene and the FRA3B fragile site, is frequently altered in carcinomas. We analyzed the expression of the FHIT gene in 21 Burkitt's lymphoma cell lines and normal lymphoid populations. Seventeen (80%) of these cell lines had a common aberrant FHIT