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Estimation of the male and female mutation rates in Duchenne muscular dystrophy (DMD)

✍ Scribed by B. Müller; C. Dechant; G. Meng; S. Liechti-Gallati; R. A. Doherty; J. F. Hejtmancik; E. Bakker; A. P. Read; M. Jeanpierre; K. H. Fischbeck; G. Romeo; U. Francke; E. Wilichowski; C. R. Greenberg; C. Broeckhoven; C. Junien; C. R. Müller; T. Grimm

Publisher
Springer
Year
1992
Tongue
English
Weight
226 KB
Volume
89
Category
Article
ISSN
0340-6717

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✦ Synopsis

We present the results of an international collaborative study aimed at estimating the ratio of male to female mutation rates in Duchenne muscular dystrophy based on the method of C. Müller and T. Grimm. With a sample size of 295, this ratio is found to be very close to 1, thus giving evidence for equal mutation rates in males and females in Duchenne muscular dystrophy.

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