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Estimation of Haplotype Frequency and Linkage Disequilibrium Parameter in the HLA System

✍ Scribed by Norikazu Yasuda


Book ID
115092909
Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
381 KB
Volume
12
Category
Article
ISSN
0001-2815

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Haplotype analysis of the linkage group
✍ K. Bender; A. MayerovΓ‘; R. Frank; C. Hiller; T. Wienker πŸ“‚ Article πŸ“… 1977 πŸ› Springer 🌐 English βš– 275 KB

The analysis of 650 HLA-A:HAL-B:Bf three-factor haplotypes revealed significant associations only between alleles of the very closely linked genes HLA-A and HLA-B, and Bf, respectively. Most striking is the highly significnat association of the rare Bf variant F1 with HLA-B18 and of S1 with HLA-B13,