The pFc' fragments of a humanized IgG 1 monoclonal antibody were generated by digestion with immobilized pepsin. These pFc' fragments were separated from F(ab') 2 fragments by affinity chromatography. The pFc' fragments corresponding to the constant region of the humanized IgG 1 monoclonal antibody
โฆ LIBER โฆ
Estimation of association constants of 42 monoclonal antibodies to human IgG epitopes using a fluorescent sequential-saturation assay
โ Scribed by Donald J. Phillips; Thomas W. Wells; Charles B. Reimer
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 652 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0165-2478
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A human monoclonal antibody to cytomegalovirus (CMV) was produced by transforming peripheral blood mononuclear cells of a patient with recent CMV infection. It is directed against a late antigen located in the nucleus of CMV infected fibroblasts at 24-72 hours postinfection and immuneprecipitates 65