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Estimating the Number of Double-Strand Breaks Formed During Meiosis from Partial Observation

✍ Scribed by Toyoizumi, Hiroshi; Tsubouchi, Hideo

Book ID: 120385822
Publisher: Mary Ann Liebert
Year: 2012
Tongue: English
Weight: 232 KB
Volume: 19
Category: Article
ISSN: 1066-5277
DOI: 10.1089/cmb.2012.0209

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## Abstract DNA double‐strand breaks (DSBs) are extremely hazardous lesions for all DNA‐bearing organisms and the mechanisms of DSB repair are highly conserved. In the eukaryotic mitotic cell cycle, DSBs are often present following DNA replication while, in meiosis, hundreds of DSBs are generated a