𝔖 Bobbio Scriptorium
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Estimating mutation rates in low-replication experiments

✍ Scribed by Alejandro Couce; Jesús Blázquez


Book ID
113809565
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
678 KB
Volume
714
Category
Article
ISSN
0027-5107

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An algorithm is described for calculating the probability distribution of the number of mutant colonies arising in a Luria-Delbrtick fluctuation experiment subject to a plating efficiency of less than 100%. A table is constructed to facilitate the estimation of spontaneous mutation rates taking into