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Esters of aminoalcohols derived from 3 - azabicyclo[ 3.2.2] nonane

โœ Scribed by Pramod P. Karkhanis; W. Lewis Nobles


Publisher
John Wiley and Sons
Year
1967
Tongue
English
Weight
316 KB
Volume
56
Category
Article
ISSN
0022-3549

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Synthesis of 2-Azabicyclo[3.2.2]nonane-D
โœ Stephan Buser; Andrea Vasella ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ German โš– 143 KB ๐Ÿ‘ 1 views

The racemic 2-azabicyclo[3.2.2]nonanes 5 and 18 were synthesized and tested as b-glycosidase inhibitors. The intramolecular Diels-Alder reaction of the masked o-benzoquinone generated from 2-(allyloxy)phenol ( 6) gave the a-keto acetal 7 which was reduced with SmI 2 to the hydroxy ketone 8. Dihydrox