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Esterase D polymorphism: Gene frequencies and family data

โœ Scribed by Heide -G. Benkmann; H. Werner Goedde

Publisher
Springer
Year
1974
Tongue
English
Weight
123 KB
Volume
24
Category
Article
ISSN
0340-6717

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๐Ÿ“œ SIMILAR VOLUMES

Esterase D polymorphism in Chinese and J
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Esterase D phenotypes have been determined in Chinese and Japanese populations in the San Francisco area. The EsD1 gene frequencies were 0.612 for the Chinese population and 0.582 for the Japanese population.

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Several regional series from Britain and 3 Asian series were typed for the Esterase D polymorphism. It was found that haemolysates up to 5 years old could be reliably typed when prepared from washed anticoagulated red blood cells. Lysates prepared from blood clots do not retain Esterase D activity q

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## Abstract Family data are useful for estimating disease risk in carriers of specific genotypes of a given gene (penetrance). Penetrance is frequently estimated assuming that relatives' phenotypes are independent, given their genotypes for the gene of interest. This assumption is unrealistic when