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Establishment of a Human Monoclonal Antibody to Hanganutziu-Deicher Antigen as a Tumor-associated Carbohydrate Antigen

✍ Scribed by Usuba, Osamu ;Fujii, Yoichi ;Miyoshi, Ichiro ;Naiki, Masaharu ;Sendo, Fujiro

Book ID
118699763
Publisher
Wiley (Blackwell Publishing)
Year
1988
Tongue
English
Weight
471 KB
Volume
79
Category
Article
ISSN
0910-5050

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## Abstract Two monoclonal antibodies (KH‐1 and KH‐2) against a transplanted fibrosarcoma (KMT‐17) in WKA rats were produced by fusing a mouse myeloma (P~3~‐X63‐Ag8.653) with spleen cells from syngeneic rats hyperimmunized with KMT‐17. Both antibodies showed complement‐dependent cytotoxicity agains