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Molecular Cloning of a Tumor-Associated Antigen Recognized by Monoclonal Antibody 3H11

✍ Scribed by Donghai Chen; Chengchao Shou

Book ID
115587160
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
108 KB
Volume
280
Category
Article
ISSN
0006-291X

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## Abstract Two monoclonal antibodies (KH‐1 and KH‐2) against a transplanted fibrosarcoma (KMT‐17) in WKA rats were produced by fusing a mouse myeloma (P~3~‐X63‐Ag8.653) with spleen cells from syngeneic rats hyperimmunized with KMT‐17. Both antibodies showed complement‐dependent cytotoxicity agains