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Establishment and characterization of androgen-independent human prostate cancer cell lines, PcBra1, PcBra2, and PcBra3

✍ Scribed by Camila B. Piantino; Juliana M. Sousa-Canavez; Marta Bellodi-Privato; Miguel Srougi; Luiz Heraldo Camara-Lopes; Gilka Jorge Figaro Gattás; Fernanda de Toledo Gonçalves; Cintia Fridman; Katia R. M. Leite


Book ID
107427207
Publisher
Society for In Vitro Biology
Year
2009
Tongue
English
Weight
275 KB
Volume
46
Category
Article
ISSN
1475-2689

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BACKGROUND. Androgen-independent growth leads to progressive prostate cancer after androgen-ablation therapy. This may be caused by altered specificity of the androgen receptor (AR), by ligand-independent stimulation of the AR, or by paracrine growth modulation by neuropeptides secreted by neuroendo