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Establishment and characterization of a new, factor-independent acute myeloid leukemia line designated Ei501

✍ Scribed by Weidmann, E; Brieger, J; Karakas, T; Maurer, U; Pascheberg, U; Hoelzer, D; Mitrou, P S; Bergmann, L

Book ID
110053482
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
746 KB
Volume
11
Category
Article
ISSN
0887-6924

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## Abstract A human leukemic cell line (THP‐1) cultured from the blood of a boy with acute monocytic leukemia is described. This cell line had Fc and C3b receptors, but no surface or cytoplasmic immunoglobulins. HLA haplotypes of THP‐1 were HLA‐A2, ‐A9, ‐B5, ‐DRW1 and ‐DRW2. The monocytic nature of