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Establishment and characteristics of a T-cell acute lymphoblastic leukemia cell line, JK-T1, with a chromosomal translocation between 8q24 and 14q13

✍ Scribed by Mitsuyoshi Urashima; Hideaki Iyori; Kouji Fujisawa; Yasutaka Hoshi; Jun-ichi Akatsuka; Kihei Maekawa


Book ID
119105535
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
501 KB
Volume
64
Category
Article
ISSN
0165-4608

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Cell lines established from T-cell leukemias have recently been reported to exhibit a chromosome translocation t(8; 14) involving proto-oncogene c-myc and the gene of the T-cell receptor a-chain(TcR-a). In this work, we have studied a case of T-cell leukemia presenting a t(8; 14)(q24;q I I) transloc