Genes that regulate apoptosis in the mou
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Barbara A. Osborne; Sallie W. Smith; Kelly A. McLaughlin; Lisa Grimm; Tilmann Ka
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Article
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1996
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John Wiley and Sons
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English
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Elimination of self-reactive T lymphocytes occurs during T-cell development in the thymus by a process known as negative selection. The mechanism that drives negative selection is apoptosis. To identify genes that regulate apoptosis in the mouse thymus, a library of negatively selected T cells was c