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Erythropoietic effects of PGE2and 2 endoperoxide analogs

โœ Scribed by D. M. Gross; J. W. Fisher

Publisher
Springer
Year
1980
Tongue
English
Weight
246 KB
Volume
36
Category
Article
ISSN
1420-682X

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Synthesis and biological evaluation of 2
Synthesis and biological evaluation of 2,3-diazabicyclo[2.2.1]heptane derivatives as prostaglandin endoperoxide analogs
โœ Sheung-Tsam Kam; Robert N. Hanson; Philip S. Portoghese ๐Ÿ“‚ Article ๐Ÿ“… 1980 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 505 KB

Three prostaglandin endoperoxide analogs that possess the 2,3-diazabicyclo[2.2.1]heptane skeleton were synthesized and evaluated for activity in human platelets and in the rat fundus. All three compounds were inactive in inhibiting or stimulating platelet aggregation. One compound possessed weak con