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Erythrocyte ghosts (Na++K+) ATPase activity in duchenne's dystrophy and myotonia

✍ Scribed by Irena Niebrój-Dobosz

Publisher
Springer
Year
1976
Tongue
English
Weight
533 KB
Volume
214
Category
Article
ISSN
0340-5354

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✦ Synopsis

In Duchenne muscular dystrophy the activity of (Na+ + K+)ATPase in erythrocyte ghosts is reduced and its reaction to ouabain is paradoxical both in low sodium and high sodium systems. No such changes were seen in a case of Becker dystrophy, in limb-girdle dystrophy, and in neurogenic atrophy of muscles. In myotonic dystrophy and congenital myotonia the activity of ATPase and its inhibition by ouabain were depressed.

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