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Erythrocyte ferritin in normal subjects and patients with abnormal iron metabolism

✍ Scribed by S. W. Peters; A. Jacobs; E. Fitzsimons


Book ID
114709990
Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
321 KB
Volume
53
Category
Article
ISSN
0007-1048

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Friedreich's ataxia (FRDA) is caused by point mutations or trinucleotide repeat expansions in both alleles of the gene encoding frataxin. Studies of frataxin homologues in lower eukaryotes suggest that mitochondrial iron accumulation may underlie the pathophysiology of FRDA. To evaluate the possible