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Erwinia asparaginase for acute lymphoblastic leukemia in children with hypersensitivity to E coli-derived asparaginase

✍ Scribed by Jame Abraham


Book ID
119219264
Publisher
Frontline Medical Communications, Inc.
Year
2012
Tongue
English
Weight
89 KB
Volume
9
Category
Article
ISSN
1548-5315

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Allergic reactions to Erwinia asparagina
✍ Amy Louise Billett; Stephen E. Sallan; Alexa Carls; Richard D. Gelber πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 556 KB

Background. Escherichia coli asparaginase is an active antileukemia agent in the treatment of childhood acute lymphoblastic leukemia. Allergic reactions occurred in 31 of 125 patients (24.8%) treated with weekly high-dose (25,000 IU/m2) intramuscular E. coli asparaginase and necessitated discontinua