Thrombotic Events Revisited in Children with Acute Lymphoblastic Leukemia: Impact of Concomitant Escherichia coli Asparaginase/Prednisone Administration

A prospective cohort study determining t

A prospective cohort study determining the prevalence of thrombotic events in children with acute lymphoblastic leukemia and a central venous line who are treated with L-asparaginase : Results of the Prophylactic Antithrombin Replacement in Kids with Acute Lymphoblastic Leukemia Treated with Asparaginase (PARKAA) Study

✍ Lesley G. Mitchell;; the PARKAA Group 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 221 KB 👁 1 views

## Abstract ## BACKGROUND Thrombotic events (TEs) are serious secondary complications in children with acute lymphoblastic leukemia (ALL) who receive L‐asparaginase (ASP) therapy; however, the prevalence of TEs has not been established. The primary objective of the Prophylactic Antithrombin Replac