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Erratum to: Phase I trial of bortezomib and dacarbazine in melanoma and soft tissue sarcoma

✍ Scribed by Andrew Poklepovic, Leena E. Youssefian, Mary Winning, Christine A. Birdsell, Nancy A. Crosby, Viswanathan Ramakrishnan, Marc S. Ernstoff, John D. Roberts

Book ID
120966770
Publisher
Springer US
Year
2013
Tongue
English
Weight
53 KB
Volume
31
Category
Article
ISSN
0167-6997

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## BACKGROUND. Cryosurgery is a therapeutic method of treating neoplastic tissue by freezing in situ to achieve devitalization. Cell death results from exposure to severe cold (below Οͺ40Β°C for at least 1 minute) as well as from the process of freezing and thawing, which disrupts cellular integrity.