## Abstract Over the past few years, the “critical body residue” approach for assessing toxicity based on bioaccumulated chemicals has evolved into a more expansive consideration of tissue residues as the dose metric when defining dose–response relationships, evaluating mixtures, developing protect
Erratum: The tissue residue approach for toxicity assessment: Findings and critical reviews from a Society of Environmental Toxicology and Chemistry Pellston Workshop
✍ Scribed by James P Meador; William J Adams; Beate I Escher; Lynn S McCarty; Anne E McElroy; Keith G Sappington
- Publisher
- Society of Environmental Toxicology and Chemistry
- Year
- 2011
- Tongue
- English
- Weight
- 31 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1551-3777
- DOI
- 10.1002/ieam.178
No coin nor oath required. For personal study only.
✦ Synopsis
At the bottom of page 3 (left side) of the Introduction, all mmol/g values should be mmol/g. The correct text is:
A large number, possibly hundreds, of nonpolar organic compounds cause mortality within a very narrow range of whole-body tissue concentrations ( 2-8 mmol/g wet weight or about 50 mmol/g lipid) in small aquatic organisms, while exposure-based metrics (e.g., lethal concentration, 50% [LC50] values) span approximately 6 orders of magnitude. The range for polar organic compounds acting by the same mode of action is also narrow, but lower ( 0.6-2 mmol/g).
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## Abstract This paper reviews the tissue residue approach (TRA) for toxicity assessment as it applies to organic chemicals and some organometallic compounds (Sn, Hg, and Pb) in aquatic organisms. Specific emphasis was placed on evaluating key factors that influence interpretation of critical body