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Erratum: Synthesis of epothilones A and B in solid and solution phase

โœ Scribed by Nicolaou, K. C.; Winssinger, N.; Pastor, J.; Ninkovic, S.; Sarabia, F.; He, Y.; Vourloumis, D.; Yang, Z.; Li, T.; Giannakakou, P.; Hamel, E.


Book ID
109784491
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
551 KB
Volume
390
Category
Article
ISSN
0028-0836

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โœ JosรฉW. Nieuwenhuijzen; Paolo G.M. Conti; Harry C.J. Ottenheijm; Joannes T.M. Lin ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 222 KB

An efficient parallel synthesis of ureas based on amino acids is described, both in solution and on solid phase, l,l'-Carbonylbisbenzotriazole 2 is used as the coupling reagent. The ureas 5 and 10 were obtained in high yield (80-100%) and purity (71-97%).