Cytotoxicity of novel unsymmetrically su
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Lynsey M. Nairn; Gayle S. Lindsay; P.M. Woster; Heather M. Wallace
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Article
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2000
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John Wiley and Sons
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English
โ 133 KB
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The cytotoxicity of two novel polyamine analogues was compared with that of a known cytotoxic drug, etoposide, in a human promyelogenous leukemic cell line. CHEN-spm showed significant acute cytotoxicity in these cells and was comparable to etoposide in terms of IC 50 value. The cell death observed