𝔖 Bobbio Scriptorium
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ERK5 signalling in prostate cancer promotes an invasive phenotype

✍ Scribed by Edwards, D R; Ramsay, A K; McCracken, S R C; Soofi, M; Fleming, J; Yu, A X; Ahmad, I; Morland, R; Machesky, L; Nixon, C


Book ID
110000838
Publisher
Nature Publishing Group
Year
2011
Tongue
English
Weight
834 KB
Volume
104
Category
Article
ISSN
0007-0920

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## Abstract Both invasion‐promoting MT1‐MMP and its physiological inhibitorTIMP‐2 play a significant role in tumorigenesis and are identified in the most aggressive cancers. Despite its antiproteolytic effects __in vitro__, clinical data suggest that TIMP‐2 expression is positively associated with