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Erk 1/2 differentially regulates the expression from the 1G/2G single nucleotide polymorphism in the MMP-1 promoter in melanoma cells

โœ Scribed by Grant B Tower; Charles C Coon; Ulrike Benbow; Matthew P Vincenti; Constance E Brinckerhoff

Book ID
117617870
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
517 KB
Volume
1586
Category
Article
ISSN
0925-4439

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โœ Ulrike Benbow; Grant B. Tower; Colby A. Wyatt; Giovanna Buttice; Constance E. Br ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 302 KB ๐Ÿ‘ 2 views

Matrix metalloproteinase-1 (MMP-1) is one of only a few enzymes with the ability to degrade the stromal collagens (types I and III) at neutral pH, and high expression of MMP-1 has been associated with aggressive and invasive cancers. We recently reported a single nucleotide insertion/deletion polymo