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Ergosterol-conferred sensitivity to amphotericin B in cultured L1210 mouse leukemia cells

✍ Scribed by Fred J. Schiffman; Joyce M. Fisher; Marco Rabinovitz

Book ID
115773591
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
456 KB
Volume
26
Category
Article
ISSN
0006-2952

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L1210 leukemia cells, because of their rapid growth rate in suspension culture and high growth fraction, are ideally suited to screen in vitro for cytotoxic compounds. Although L1210 cells may mimic rapidly growing tumors, they have not been effective in selecting agents active against slow growing