## Abstract Binding constants and binding site sizes for the interactions of the polyamines spermine (+4), spermidine (+3), and putrecine (+2) with helical DNA have been determined as a function of ionic conditions and temperature by equilibrium dialysis using ^14^Cβlabeled polyamines. In addition,
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EQUILIBRIUM DIALYSIS STUDIES OF HORMONE-NEUROPHYSIN BINDING
β Scribed by Victor J. Hruby; Arno F. Spatola; Jay A. Glasel; Jeffrey F. McKelvy
- Book ID
- 114881834
- Publisher
- John Wiley and Sons
- Year
- 1975
- Tongue
- English
- Weight
- 345 KB
- Volume
- 248
- Category
- Article
- ISSN
- 0890-6564
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In recent years there has been great interest in using hexammine cobalt(II1) as an isovalent analogue of spermidine. Hexammine cobalt(II1) qualitatively mimics spermidine in many of its physical effects on nucleic acids. Quantitatively, however, there are often large differences in the effects of th