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Equal proportion of adult male and female homozygous for the 677C → T mutation in the methylenetetrahydrofolate reductase polymorphism

✍ Scribed by Cheryl A.M. Anderson; Arne Lund Jorgensen; Samir Deeb; Dale McLerran; Shirley A.A. Beresford; Arno G. Motulsky


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
52 KB
Volume
134A
Category
Article
ISSN
1552-4825

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Methylenetetrahydrofolate reductase (MTH
✍ Rady, Peter L.; Tyring, Stephen K.; Hudnall, S. David; Vargas, Trini; Kellner, L 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 36 KB 👁 2 views

The polymorphic mutation C677T in the gene of MTHFR is considered a risk mutation for spina bifida and vascular disease. Another common mutation on the MTHFR gene, A1298C, has also been described as another risk mutation. We studied the frequencies of these two mutations on DNA samples from healthy