𝔖 Bobbio Scriptorium
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Epstein-Barr virus-specific cytotoxic T cell responses in rheumatoid arthritis patients

✍ Scribed by J. S. H. Gaston; A. B. Rickinson; M. A. Epstein

Publisher
Springer
Year
1982
Tongue
English
Weight
445 KB
Volume
2
Category
Article
ISSN
0172-8172

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✦ Synopsis

The level of Epstein-Barr (EB) virus-specific cytotoxic T cell responsiveness was measured in 21 patients with active, progressive rheumatoid arthritis (RA). A significant number (8 out of 20) of EB virus sero-positive patients showed a markedly impaired responsiveness when compared with a control group of healthy individuals. Serological responses of the RA patients to EB virus antigens were not significantly different from the control group. The defect in EB virus-specific cellular immunity shown by these results is of interest in the light of previous evidence of an alteration in the virus-host balance in RA patients.

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