Epstein-Barr virus interactions with the Bcl-2 protein family and apoptosis in human tumor cells
β Scribed by Qin Fu, Chen He, Zheng-rong Mao
- Book ID
- 119923351
- Publisher
- SP Zhejiang University Press
- Year
- 2013
- Tongue
- English
- Weight
- 514 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1673-1581
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The Epstein-Barr virus (EBV) open reading frame BHRF1, a homologue of the oncogene bcl-2, was cloned from a patient with nasopharyngeal carcinoma (NPC) and overexpressed in Escherichia coli. The resulting recombinant BHRF1 fusion protein, with an apparent molecular weight of 35 KD, was used as antig
## Abstract We have recently reported that the naturally occurring spliced variant of Hepatitis B virus protein, HBSP, displayed proapoptotic activity through its BH3 domain. To investigate whether the BH3 domain in HBSP interacted with Bclβ2 family of proteins, HBSP and Bclβ2 family of proteins we