Epstein-Barr virus DNA detection in the diagnosis of nasopharyngeal carcinoma
โ Scribed by Yoke-Yeow Yap; Shahid Hassan; Melissa Chan; Pua Kin Choo; Manickam Ravichandran
- Book ID
- 116812484
- Publisher
- SAGE Publications
- Year
- 2007
- Tongue
- English
- Weight
- 109 KB
- Volume
- 136
- Category
- Article
- ISSN
- 0194-5998
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๐ SIMILAR VOLUMES
Immunologic studies of Epstein-Barr virus (EBV) have implicated EBV in undifferentiated and partially differentiated, non-keratinizing nasopharyngeal carcinoma (NPC). Patients with the well-differentiated, keratinizing form of NPC have EBV serologic patterns similar to those of control populations.
## RESULTS. In specimens from 107 patients with NPC, EBV was detected by PCR in 2 Department of Pathology, the Johns Hopkins 97 cases (90.7%) and by EBER in situ hybridization in 105 cases (98.1%). In speci-