Epoxidation of 7-double bond of cholesta-5,7-dien-3β-OL by permanganate

✍ Scribed by Mario Anastasia; Alberto Fiecchi; Antonio Scala

• Book ID: 104246395
• Publisher: Elsevier Science
• Year: 1979
• Tongue: French
• Weight: 228 KB
• Volume: 20
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)95398-5

✦ Synopsis

The 5,7-diene system of ring B unsaturated steroids is transformed by neutral or alkaline permanganate mainly into a 5s,6+dihydroxy-7n,8+epoxide and minor amounts of more polar compounds.

In a recent paper' It was reported that 3,/+acetoxy-5d,6a,7*,8/-tetrahydro--xycholestane (mp 196'C, a D go, IJ