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Epitope mapping of LB509, a monoclonal antibody directed against human α-synuclein

✍ Scribed by Ross Jakes; R.Anthony Crowther; Virginia M.-Y. Lee; John Q. Trojanowski; Takeshi Iwatsubo; Michel Goedert

Book ID
117477793
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
266 KB
Volume
269
Category
Article
ISSN
0304-3940

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Epitope mapping of a monoclonal antibody
Epitope mapping of a monoclonal antibody directed against the α-subunit of phosphofructokinase-1 from Saccharomyces cerevisiae by screening phage display libraries
✍ Margrit Hollborn; Jürgen Kirchberger; Gerd Birkenmeier; Gerhard Kopperschläger 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 90 KB

Phosphofructokinase-1 from Saccharomyces cerevisiae is composed of two types of subunits, a and b. Subunit-specific monoclonal antibodies were raised to elucidate structural and functional properties of both subunits. One monoclonal antibody, a-F3, binds to an epitope either at the C-terminal or at