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Epitope mapping by screening of phage display libraries of a monoclonal antibody directed against the receptor binding domain of human α2-macroglobulin

✍ Scribed by Gerd Birkenmeier; Awad A Osman; Gerhard Kopperschläger; Thomas Mothes


Book ID
117108287
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
687 KB
Volume
416
Category
Article
ISSN
0014-5793

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Epitope mapping of a monoclonal antibody
✍ Margrit Hollborn; Jürgen Kirchberger; Gerd Birkenmeier; Gerhard Kopperschläger 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 90 KB

Phosphofructokinase-1 from Saccharomyces cerevisiae is composed of two types of subunits, a and b. Subunit-specific monoclonal antibodies were raised to elucidate structural and functional properties of both subunits. One monoclonal antibody, a-F3, binds to an epitope either at the C-terminal or at